Recombinant Integrin α2 Monoclonal Antibody
Product Specifications
Background
ITGA2 (integrin subunit alpha 2) Homo sapiens This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.
Abbreviation
Integrin α2
UniProt
P17301
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human Integrin α2 protein
Target
HPA; VLA; VLAA; ITGA; BR; CD49B; GPIa; HPA-5; VLA-2; VLAA2; ITGA2; gpIa; &alpha-2 integrin-n; VLA-2α alpha 2 (CD49B alpha 2 subunit of VLA 2 receptor) ; CD 49b; CD49 antigen like family member B; CD49 antigen-like family member B; CD49b antigen; Collagen receptor; deficiency of; DX5; Glycoprotein Ia deficiency included; GP Ia; GP Ia deficiency; HPA 5 included; HPA5 included; Human platelet alloantigen system 5; included; Integrin; Integrin alpha 2; Integrin alpha II; Integrin alpha-2; ITA2; Platelet alloantigen Br (a) ; Platelet antigen Br; Platelet glycoprotein GPIa; Platelet glycoprotein Ia; Platelet glycoprotein Ia/IIa; Platelet membrane glycoprotein Ia; Platelet receptor for collagen; Very late activation protein 2 receptor alpha 2 subunit; VLA 2; VLA 2 alpha chain; VLA 2 subunit alpha; VLA2; VLA2 receptor alpha 2 subunit; VLA-2 subunit alpha; Integrin α2
Clonality
Monoclonal,Recombinant
Clone
4D10
Conjugation
Unconjugated
Applications
IHC
Field of Research
Signal Transduction; Cancer; Metabolism
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:200-1:1000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG, κ
Available Sizes
Frequently Asked Questions
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