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Recombinant Integrin α2 Monoclonal Antibody

Product Specifications

Background

ITGA2 (integrin subunit alpha 2) Homo sapiens This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.

Abbreviation

Integrin α2

UniProt

P17301

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human Integrin α2 protein

Target

HPA; VLA; VLAA; ITGA; BR; CD49B; GPIa; HPA-5; VLA-2; VLAA2; ITGA2; gpIa; &alpha-2 integrin-n; VLA-2α alpha 2 (CD49B alpha 2 subunit of VLA 2 receptor) ; CD 49b; CD49 antigen like family member B; CD49 antigen-like family member B; CD49b antigen; Collagen receptor; deficiency of; DX5; Glycoprotein Ia deficiency included; GP Ia; GP Ia deficiency; HPA 5 included; HPA5 included; Human platelet alloantigen system 5; included; Integrin; Integrin alpha 2; Integrin alpha II; Integrin alpha-2; ITA2; Platelet alloantigen Br (a) ; Platelet antigen Br; Platelet glycoprotein GPIa; Platelet glycoprotein Ia; Platelet glycoprotein Ia/IIa; Platelet membrane glycoprotein Ia; Platelet receptor for collagen; Very late activation protein 2 receptor alpha 2 subunit; VLA 2; VLA 2 alpha chain; VLA 2 subunit alpha; VLA2; VLA2 receptor alpha 2 subunit; VLA-2 subunit alpha; Integrin α2

Clonality

Monoclonal,Recombinant

Clone

4D10

Conjugation

Unconjugated

Applications

IHC

Field of Research

Signal Transduction; Cancer; Metabolism

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

IHC 1:200-1:1000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG, κ

Available Sizes

Frequently Asked Questions

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