Recombinant PAI-1 Monoclonal Antibody

This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Plasminogen activator inhibitor; PLANH; SERPINE; Serpin E; PAI; PAI-1; PAI1; PLANH1; SERPINE1; Plasminogen activator inhibitor 1; Endothelial plasminogen activator inhibitor; Serpin E1; Clade E; Nexin; PAI 1; Plasminogen activator inhibitor type 1; Serine (or cysteine) proteinase inhibitor; Serine (or cysteine) proteinase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1; Serpin peptidase inhibitor clade E; Serpin peptidase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1; Serpine 1; PAI-1