Recombinant Cdk9 Monoclonal Antibody
Product Specifications
Background
CDK9 (cyclin dependent kinase 9) Homo sapiens The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.
Abbreviation
Cdk9
UniProt
P50750
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human Cdk9 protein
Target
CDK; CTK; CDC2L; CDK9; C-2k; CDC2L4; CTK1; PITALRE; TAK; Cdk9
Clonality
Monoclonal,Recombinant
Clone
8B5
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cell Biology; Microbiology; Epigenetics and Nuclear Signaling; Immunology
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:200-1:1000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG, κ
Available Sizes
Curated Selection
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