Recombinant Collagen VI Monoclonal Antibody
Product Specifications
Background
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1 (VI), alpha2 (VI), and alpha3 (VI) chains. The alpha2 (VI) and alpha3 (VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1 (VI) chain) . Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.
Abbreviation
Collagen VI
UniProt
P12109
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human Collagen VI protein
Target
COL6A; BTHLM; UCHMD; COL6A1; BTHLM1; OPLL; UCHMD1; Collagen alpha-1 (VI) chain; COL6A1
Clonality
Monoclonal,Recombinant
Clone
7B3
Conjugation
Unconjugated
Applications
IHC
Field of Research
Signal Transduction; Cancer
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:200-1:1000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG, κ
Available Sizes
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