Recombinant GCN2 Monoclonal Antibody
Product Specifications
Background
This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.
Abbreviation
GCN2
UniProt
Q9P2K8
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human GCN2 protein
Target
GCN; PVOD; KIAA; Eukaryotic Translation Initiation Factor 2 alpha kinase; Eukaryotic translation initiation factor 2-alpha kinase; E2AK; MGCN; EIF2AK; EIF2AK4; GCN2; PVOD2; E2AK4; Eukaryotic Translation Initiation Factor 2 alpha kinase 4; Eukaryotic translation initiation factor 2-alpha kinase 4; GCN2 eIF2alpha kinase; GCN2 like protein; GCN2-like protein; MGCN2; KIAA1338; GCN2
Clonality
Monoclonal,Recombinant
Clone
2D10
Conjugation
Unconjugated
Applications
IHC
Field of Research
Epigenetics and Nuclear Signaling; Signal Transduction
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:100-1:500
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG, κ
Available Sizes
Curated Selection
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