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Recombinant GCN2 Monoclonal Antibody

Product Specifications

Background

This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.

Abbreviation

GCN2

UniProt

Q9P2K8

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human GCN2 protein

Target

GCN; PVOD; KIAA; Eukaryotic Translation Initiation Factor 2 alpha kinase; Eukaryotic translation initiation factor 2-alpha kinase; E2AK; MGCN; EIF2AK; EIF2AK4; GCN2; PVOD2; E2AK4; Eukaryotic Translation Initiation Factor 2 alpha kinase 4; Eukaryotic translation initiation factor 2-alpha kinase 4; GCN2 eIF2alpha kinase; GCN2 like protein; GCN2-like protein; MGCN2; KIAA1338; GCN2

Clonality

Monoclonal,Recombinant

Clone

2D10

Conjugation

Unconjugated

Applications

IHC

Field of Research

Epigenetics and Nuclear Signaling; Signal Transduction

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

IHC 1:100-1:500

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product MSDS

https://789.bio/eb/6GQPmxqc

Isotype

IgG, κ

Available Sizes

Curated Selection

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