Recombinant GCN2 Monoclonal Antibody

This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.

GCN; PVOD; KIAA; Eukaryotic Translation Initiation Factor 2 alpha kinase; Eukaryotic translation initiation factor 2-alpha kinase; E2AK; MGCN; EIF2AK; EIF2AK4; GCN2; PVOD2; E2AK4; Eukaryotic Translation Initiation Factor 2 alpha kinase 4; Eukaryotic translation initiation factor 2-alpha kinase 4; GCN2 eIF2alpha kinase; GCN2 like protein; GCN2-like protein; MGCN2; KIAA1338; GCN2