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Recombinant PDE1B Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Abbreviation

PDE1B

UniProt

Q01064

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human PDE1B protein

Target

PDE1B; HEL-S-79p; PDE1B1; PDES1B

Clonality

Monoclonal,Recombinant

Clone

5B2

Conjugation

Unconjugated

Applications

WB

Field of Research

Signal Transduction

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

WB 1:1000-1:5000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

59 kDa

Observed Molecular Weight

59 kDa

Isotype

IgG, κ

Available Sizes

Frequently Asked Questions

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