Recombinant PAKγ Monoclonal Antibody
Product Specifications
Background
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
Abbreviation
PAKγ
UniProt
Q13177
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human PAKγ protein
Target
PAK; PAK2; PAK65; PAKgamma;65-KD; CB422; C-t-PAK2; EC 2.7.11.1; Gamma PAK; Gamma-PAK; hPAK65; Kinase; p21 (CDKN1A) activated kinase 2; p21 (CDKN1A) -activated kinase 2a; p21 activated kinase 2; p21 protein (Cdc42/Rac) -activated kinase 2; p21 protein Cdc42 Rac activated kinase 2; p21-activated kinase; p21-activated kinase 2; p21-activated protein kinase I; p21CDKN1A activated kinase 2; p27; p34; p58; p65PAK; PAK 2; PAK-2; PAK-2p34; S6 H4 kinase; S6/H4 kinase; Serine threonine protein kinase PAK 2; Serine/threonine protein kinase PAK 2; PAK2
Clonality
Monoclonal,Recombinant
Clone
5D5
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cell Biology; Microbiology; Signal Transduction; Cancer; Neuroscience
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:200-1:1000; WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
58 kDa
Observed Molecular Weight
58 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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