Recombinant Galectin-3 Monoclonal Antibody

This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.

MAC; Galactose-specific lectin; Galactoside-Binding Soluble; Galectin; Lectin L; GAL; CBP; LGALS3; CBP35; GAL3; GALBP; GALIG; L31; LGALS2; MAC2; Galactoside-Binding Soluble 3; Lectin; Galectin-3; Gal-3; L-31;35 kDa lectin; CBP 35; Galactose-specific lectin 3; IgE-binding protein; Laminin-binding protein; Lectin L-29; Mac-2 antigen; Carbohydrate binding protein 35; Carbohydrate-binding protein 35; galactose binding; galactoside binding soluble 3; Galactoside-binding protein; galectin 3; Galectin 3 internal gene; Galectin3; GBP; IgE binding protein; included; L 31; L 34; L-34 galactoside-binding lectin; Lectin; Galactoside-Binding Soluble 3; LEG3; MAC 2 antigen; Mac-2; Macrophage galactose-specific lectin; MGC105387; P35; soluble 3; Galectin-3