Recombinant BRD4 Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t (15;19) (q13; p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
Abbreviation
BRD4
UniProt
O60885
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human BRD4 protein
Target
BRD; HUNK; bromodomain containing; HUNK1bromodomain-containing protein; BRD4; CAP; HUNK1; HUNKI; MCAP; bromodomain containing 4; HUNK1bromodomain-containing protein 4; BRD4-NUT FUSION; BRD4-NUT fusion oncoprotein; bromodomain containing protein 4; Bromodomain-containing protein 4; chromosome associated protein; Mitotic chromosome-associated protein; Protein HUNK1; BRD4
Clonality
Monoclonal,Recombinant
Clone
9D15
Conjugation
Unconjugated
Applications
IHC
Field of Research
Epigenetics and Nuclear Signaling; Cancer
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:100-1:200
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG, κ
Available Sizes
Curated Selection
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