Recombinant TXNIP Monoclonal Antibody

This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants.

VDUP; Thioredoxin-binding protein; Vitamin D3-Upregulated Protein; Vitamin D3 up-regulated protein; ARRDC; HHCPA; TXNIP; ARRDC6; EST01027; HHCPA78; THIF; VDUP1; Thioredoxin Interacting Protein; Vitamin D3-Upregulated Protein 1; Thioredoxin-interacting protein; Thioredoxin-binding protein 2; Vitamin D3 up-regulated protein 1; TXNIP