Recombinant Dnmt3a Monoclonal Antibody
Product Specifications
Background
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
Abbreviation
Dnmt3a
UniProt
Q9Y6K1
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human Dnmt3a protein
Target
DNMT3A; DNMT3A2; M.HsaIIIA; TBRS; DNA methyltransferase 3 alpha; DNA (cytosine 5) methyltransferase 3 alpha; DNA (cytosine 5) methyltransferase 3A; DNA (cytosine-5) -methyltransferase 3A; DNA cytosine methyltransferase 3A2; DNA methyltransferase 3a; DNA methyltransferase HsaIIIA; DNA MTase HsaIIIA|DNA cytosine methyltransferase 3 alpha|DNA cytosine methyltransferase 3A2|DNA methyltransferase HsaIIIA; DNA MTase HsaIIIA; DNM3A; DNMT; DNMT 3a; M.HsaIIIA; MCMT; OTTHUMP00000201149; DNM3A
Clonality
Monoclonal,Recombinant
Clone
9D12
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Epigenetics and Nuclear Signaling
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:100-1:500; WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product MSDS
https://789.bio/eb/s3cQo7Fx
Calculated Molecular Weight
102 kDa
Observed Molecular Weight
130 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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