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Recombinant Dnmt3a Monoclonal Antibody

Product Specifications

Background

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.

Abbreviation

Dnmt3a

UniProt

Q9Y6K1

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human Dnmt3a protein

Target

DNMT3A; DNMT3A2; M.HsaIIIA; TBRS; DNA methyltransferase 3 alpha; DNA (cytosine 5) methyltransferase 3 alpha; DNA (cytosine 5) methyltransferase 3A; DNA (cytosine-5) -methyltransferase 3A; DNA cytosine methyltransferase 3A2; DNA methyltransferase 3a; DNA methyltransferase HsaIIIA; DNA MTase HsaIIIA|DNA cytosine methyltransferase 3 alpha|DNA cytosine methyltransferase 3A2|DNA methyltransferase HsaIIIA; DNA MTase HsaIIIA; DNM3A; DNMT; DNMT 3a; M.HsaIIIA; MCMT; OTTHUMP00000201149; DNM3A

Clonality

Monoclonal,Recombinant

Clone

9D12

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Epigenetics and Nuclear Signaling

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

IHC 1:100-1:500; WB 1:2000-1:10000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

102 kDa

Observed Molecular Weight

130 kDa

Isotype

IgG, κ

Available Sizes

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