Recombinant CD11c Monoclonal Antibody
Product Specifications
Background
ITGAX (integrin subunit alpha X) Homo sapiens This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4) . The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.
Abbreviation
CD11c
UniProt
P20702
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human CD11c protein
Target
SLEB; Leukocyte adhesion receptor p150+; ITGAX; CD11C; SLEB6; CD11 antigen-like family member C; Integrin alpha-X; Leukocyte adhesion receptor p150+95; p150-95; CR4; integrin &alpha-X-X; CD11c
Clonality
Monoclonal,Recombinant
Clone
12F11
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Signal Transduction; Immunology; Stem Cells
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:200-1:1000; WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
128 kDa
Observed Molecular Weight
145 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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