Recombinant p53 (Acetyl Lys382) Monoclonal Antibody
Product Specifications
Background
TP53 (tumor protein p53) Homo sapiens This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277) .
Abbreviation
P53
UniProt
P04637
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human p53 (Acetyl Lys382) protein
Target
BCC; LFS; TRP; BMFS; Antigen NY-CO; Tumor protein; Phosphoprotein p; Tumor suppressor p; Mutant tumor protein; Cellular tumor antigen p; Transformation related protein; BCC7; LFS1; P53; TRP53; TP53; BMFS5; Antigen NY-CO-13; Cellular tumor antigen p53; FLJ92943; Mutant tumor protein 53; p53 tumor suppressor; Phosphoprotein p53; Transformation related protein 53; Tumor protein 53; Tumor protein p53; Tumor suppressor p53; BCC7; LFS1; P53; TRP53; tumor protein p53; Antigen NY-CO-13; BCC7; Cellular tumor antigen p53; FLJ92943; LFS1; Mutant tumor protein 53; p53; p53 tumor suppressor; P53; Phosphoprotein p53; Tp53; Transformation related protein 53; TRP53; Tumor protein 53; Tumor protein p53; Tumor suppressor p53; p53
Clonality
Monoclonal,Recombinant
Clone
12F5
Conjugation
Unconjugated
Applications
WB
Field of Research
Cell Biology; Epigenetics and Nuclear Signaling; Cancer
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product MSDS
https://789.bio/eb/uF9MM5di
Calculated Molecular Weight
44 kDa
Observed Molecular Weight
53 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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