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Recombinant BIRC2 Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Abbreviation

BIRC2

UniProt

Q13490

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human BIRC2 protein

Target

RNF; API; cIAP; BIRC; c-IAP; API1; HIAP2; Hiap-2; MIHB; RNF48; c-IAP1; cIAP1; BIRC2; BIRC2

Clonality

Monoclonal,Recombinant

Clone

11G2

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cell Biology; Cancer; Metabolism

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

IHC 1:200-1:1000; WB 1:2000-1:10000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

70 kDa

Observed Molecular Weight

70 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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