Recombinant Phospho-Smad3 (Ser423, Ser425) Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.
Abbreviation
Smad3
UniProt
P84022
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
A synthetic peptide corresponding to residues around (Ser423, Ser425) of Human Phospho-Smad3
Target
LDS; MAD; HSPC; JV15; MADH; MAD homolog; SMAD family member; Mothers against DPP homolog; Mothers against decapentaplegic homolog; hMAD; hSMAD; HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MADH3; hMAD-3; hSMAD3; MAD homolog 3; Mad3; Mothers against decapentaplegic homolog 3; Mothers against DPP homolog 3; SMAD 3; SMAD family member 3; SMAD3; DKFZP586N0721; DKFZp686J10186; hMAD 3; JV15 2; JV152; MAD (mothers against decapentaplegic Drosophila) homolog 3; Mad homolog JV15 2; Mad protein homolog; MADH 3; MGC60396; SMA and MAD related protein 3; SMAD
Clonality
Monoclonal,Recombinant
Clone
6H9
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Signal Transduction; Epigenetics and Nuclear Signaling; Stem Cells; Cancer; Metabolism
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:200-1:1000; WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
48 kDa
Observed Molecular Weight
52 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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