Recombinant Phospho-CaMKII α, β (Thr286) Monoclonal Antibody
Product Specifications
Background
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca (2+) /calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM) -dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
Abbreviation
CaMKII α, β
UniProt
Q9UQM7; Q13554
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide corresponding to residues around (Thr286) of Human Phospho-CaMKII α, β
Target
KIAA; CAMK2A; CAMKA; KIAA0968; Alpha CaMKII; Calcium calmodulin dependent protein kinase II; Calcium/calmodulin dependent protein kinase II alpha B subunit; Calcium/calmodulin dependent protein kinase type II alpha chain; Calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha; Calcium/calmodulin-dependent protein kinase II alpha; Calcium/calmodulin-dependent protein kinase II-alpha; Calcium/calmodulin-dependent protein kinase type II subunit alpha; Calcium/calmodulin-dependent protein kinase type IIA; CaM kinase II alpha chain; CaM kinase II alpha subunit; CaM kinase II subunit alpha; CaMK II alpha subunit; CaMKII; CaMK-II subunit alpha; CaMKIINalpha; EC 2.7.11.17; KCC2A; MGC123320; MGC139375; MGC155201; mKIAA0968; PK2CDD; PKCCD; R74975; zgc:112538; zgc:123320; CaMKIIα/β
Clonality
Monoclonal,Recombinant
Clone
6H4
Conjugation
Unconjugated
Applications
WB
Field of Research
Neuroscience; Signal Transduction; Cardiovascular; Cancer; Metabolism
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product MSDS
https://789.bio/eb/thG0CuXy
Calculated Molecular Weight
54 kDa
Observed Molecular Weight
54 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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