Recombinant Phospho-TBK1 (Ser172) Monoclonal Antibody
Product Specifications
Background
The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.
Abbreviation
TBK1
UniProt
Q9UHD2
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide corresponding to residues around (Ser172) of Human Phospho-TBK1
Target
TBK; FTDALS; TBK1; FTDALS4; NAK; T2K
Clonality
Monoclonal,Recombinant
Clone
6H2
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction; Epigenetics and Nuclear Signaling
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
84 kDa
Observed Molecular Weight
84 kDa
Isotype
IgG, κ
Available Sizes
Frequently Asked Questions
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