Recombinant Phospho-Tau (Ser396) Monoclonal Antibody
Product Specifications
Background
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Abbreviation
Tau
UniProt
P10636
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide corresponding to residues around (Ser396) of Human Phospho-Tau
Target
FTDP; PPP1R; DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU; MAPT; Microtubule-Associated Protein Tau; Neurofibrillary Tangle Protein; Paired Helical Filament-Tau; PHF-Tau; pMAPT/pTAU; TAU and MAPT; N/A; AI413597; AW045860; FLJ31424; FTDP 17; G protein beta1/gamma2 subunit interacting factor 1; included; MGC134287; MGC138549; MGC156663; Microtubule associated protein tau; Microtubule associated protein tau isoform 4; Mtapt; Paired helical filament tau; PHF tau; Protein phosphatase 1; pTau; regulatory subunit 103; RNPTAU; Tauopathy and respiratory failure
Clonality
Monoclonal,Recombinant
Clone
11A4
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Neuroscience; Signal Transduction
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:200-1:1000; WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
79 kDa
Observed Molecular Weight
55-130 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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