Recombinant ApoE Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
Abbreviation
ApoE
UniProt
P02649
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human ApoE protein
Target
MGC; LDLCQ; APOE; AD2; APO-E; ApoE4; LDLCQ5; LPG; apolipoprotein E3; MGC1571; Apolipoprotein E; ApoE
Clonality
Monoclonal,Recombinant
Clone
11A3
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Neuroscience; Cardiovascular; Stem Cells; Signal Transduction; Developmental Biology; Cancer; Metabolism
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:500-1:2000; WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
36 kDa
Observed Molecular Weight
36 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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