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Recombinant Phospho-EGFR (Tyr1068) Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

Abbreviation

EGFR

UniProt

P00533

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

A synthetic peptide corresponding to residues around (Tyr1068) of Human Phospho-EGFR

Target

PIG; HER; Proto-oncogene c-ErbB; Receptortyrosine-protein kinase erbB; Receptor tyrosine-protein kinase erbB; NISBD; EGFR; ERBB; ERBB1; HER1; NISBD2; PIG61; mENA; ErbB-1; Receptortyrosine-protein kinase erbB-1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1; NISBD2; epidermal growth factor receptor; ERBB; ERBB1; HER1; mENA; NISBD2; PIG61; Avian erythroblastic leukemia viral (v erb b) oncogene homolog; Cell growth inhibiting protein 40; Cell proliferation inducing protein 61; EGF R; Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog) ; Epidermal growth factor receptor (erythroblastic leukemia viral (v erb b) oncogene homolog avian) ; ErbB1; ERBB; erb-b2 receptor tyrosine kinase 1; Errp; Oncogen ERBB; Receptor tyrosine protein kinase ErbB 1; SA7; Species antigen 7; Urogastrone; v-erb-b Avian erythroblastic leukemia viral oncogen homolog; wa2; Wa5

Clonality

Monoclonal,Recombinant

Clone

11A2

Conjugation

Unconjugated

Applications

WB

Field of Research

Signal Transduction; Cancer

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

WB 1:2000-1:10000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

134 kDa

Observed Molecular Weight

175 kDa

Isotype

IgG, κ

Available Sizes

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