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Recombinant OLIG2 Monoclonal Antibody

Product Specifications

Background

This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t (14;21) (q11.2; q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome.

Abbreviation

OLIG2

UniProt

Q13516

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human OLIG2 protein

Target

OLIG; RACK; BHLHB; OLIGO; bHLHe; PRKCBP; OLIG2; BHLHB1; OLIGO2; PRKCBP2; RACK17; bHLHe19; OLIG2

Clonality

Monoclonal,Recombinant

Clone

12G13

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Neuroscience; Epigenetics and Nuclear Signaling; Stem Cells

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

IHC 1:200-1:1000; WB 1:2000-1:10000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

32 kDa

Observed Molecular Weight

38 kDa

Isotype

IgG, κ

Available Sizes

Frequently Asked Questions

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