Recombinant Nucleophosmin Monoclonal Antibody
Product Specifications
Background
This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
Abbreviation
Nucleophosmin
UniProt
P06748
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human Nucleophosmin protein
Target
B23; NPM; NPM1; Nucleophosmin
Clonality
Monoclonal,Recombinant
Clone
12G5
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Epigenetics and Nuclear Signaling
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:200-1:1000; WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
33 kDa
Observed Molecular Weight
38 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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