Recombinant Cofilin Monoclonal Antibody
Product Specifications
Background
Cofilin 1 (CFL1) Homo sapiens The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
Abbreviation
Cofilin
UniProt
P23528
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human Cofilin protein
Target
COF; epididymis secretory protein Li; HEL-S; CFL1; CFL; HEL-S-15; cofilin; cofilin-1;18 kDa phosphoprotein; CFL 1; COF1; Cofilin 1; Cofilin 1 non muscle; Cofilin non muscle isoform; epididymis secretory protein Li 15; N-Cofilin; non-muscle isoform; p18; Cofilin
Clonality
Monoclonal,Recombinant
Clone
11D14
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Signal Transduction; Neuroscience; Cancer; Cardiovascular
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:20000-1:50000; WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
19 kDa
Observed Molecular Weight
19 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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