Recombinant RhoA Monoclonal Antibody
Product Specifications
Background
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.
Abbreviation
RhoA
UniProt
P61586
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human RhoA protein
Target
ARH; RHOH; ARH12; ARHA; RHO12; RHOH12; Rho; RHOA; EDFAOB; ARH12; EDFAOB; RHO12; RHOH12; Aplysia ras related homolog 12; H 12; H12; Oncogene RHO H12; ras homolog family member A; Ras homolog gene family member A; Rho A; Rho cDNA clone 12; RHO H12; Small GTP binding protein Rho A; Transforming protein Rho A; Transforming protein RhoA; Rho A
Clonality
Monoclonal,Recombinant
Clone
11D10
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Signal Transduction; Cancer
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:200-1000; WB 1:1000-5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
21 kDa
Observed Molecular Weight
21 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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