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Recombinant PI3-Kinase p85 α Monoclonal Antibody

Product Specifications

Background

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms.

Abbreviation

PI3-Kinase p85 α

UniProt

P27986

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human PI3-Kinase p85 α protein

Target

GRB; IMD; AGM; PIK3R; AGM7; GRB1; IMD36; p85; p85-ALPHA; PI3 Kinase p85 alpha; PIK3R1; p85 alpha; P85A; Phosphatidylinositol 3 kinase; Phosphatidylinositol 3 kinase associated p 85 alpha; Phosphatidylinositol 3 kinase regulatory 1; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; Phosphatidylinositol 3-kinase regulatory subunit alpha; Phosphoinositide 3 kinase; PI3 kinase p85 subunit alpha; PI3K; PI3K regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3-kinase subunit p85-alpha; polypeptide 1 (p85 alpha) ; PtdIns 3 kinase p85 alpha; PtdIns-3-kinase regulatory subunit alpha; PtdIns-3-kinase regulatory subunit p85-alpha; regulatory subunit; regulatory subunit 1 (alpha) ; PI3 Kinase P85α

Clonality

Monoclonal,Recombinant

Clone

11D9

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Signal Transduction; Cancer; Immunology; Metabolism

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

IHC 1:200-1000; WB 1:1000-5000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

84 kDa

Observed Molecular Weight

84 kDa

Isotype

IgG, κ

Available Sizes

Frequently Asked Questions

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