Recombinant Histone H4 Monoclonal Antibody
Product Specifications
Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33.
Abbreviation
Histone H4
UniProt
P62805
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human Histone H4 protein
Target
H4F; methyl histone H; methylated histone H; HIST2H; HIST1H; HISTH4H; histone H; HIST2H4B; H4/o; histone H4; HIST1H4A; FO108; H4/p; HIST1H4; Hist4h4; HISTH4H4; methyl histone H4; methylated histone H4; H4/A; H4FA; H4/I; H4FI; HIST1H4B; H4/G; H4FG; HIST1H4C; H4/B; H4FB; HIST1H4D; H4/J; H4FJ; HIST1H4E; H4/C; H4FC; HIST1H4F; H4/H; H4FH; HIST1H4H; H4/M; H4FM; HIST1H4I; H4/E; H4FE; H4/D; H4FD; HIST1H4K; H4/K; H4FK; HIST1H4L; H4/N; H4F2; H4FN; HIST2H4; HIST2H4A; H4; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4-16; A; I; H4B; H4J; H4H; H4M; H4E; HIST1H4J; H4D; H4C; H4/p; histone H4; HIST1H4B H4/I
Clonality
Monoclonal,Recombinant
Clone
10F13
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Epigenetics and Nuclear Signaling
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:200-1000; WB 1:1000-5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
11 kDa
Observed Molecular Weight
11 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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