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Recombinant Aurora A Monoclonal Antibody

Product Specifications

Background

Aurora A (AURKA) Homo sapiens The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.

Abbreviation

Aurora A

UniProt

O14965

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human Aurora A protein

Target

ARK; AYK; IAK; AIRK; PPP1R; AURKA/AURKB/AURKC; PPP1R47; STK7; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6; AURKA; ARK-1; Aurora 2; Aurora A; Aurora kinase A; Aurora/IPL1 like kinase; Aurora/IPL1-related kinase 1; AURORA2; Aurora-related kinase 1; Breast tumor-amplified kinase; hARK1; IPL1 related kinase; MGC34538; OTTHUMP00000031340; OTTHUMP00000031341; OTTHUMP00000031342; OTTHUMP00000031343; OTTHUMP00000031344; OTTHUMP00000031345; OTTHUMP00000166071; OTTHUMP00000166072; Protein phosphatase 1; regulatory subunit 47; Serine/threonine kinase 15; Serine/threonine kinase 6; Serine/threonine-protein kinase 15; Serine/threonine-protein kinase 6; Serine/threonine-protein kinase aurora-A

Clonality

Monoclonal,Recombinant

Clone

10F12

Conjugation

Unconjugated

Applications

WB

Field of Research

Cell Biology; Signal Transduction; Epigenetics and Nuclear Signaling; Cancer

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

WB 1:1000-5000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

45 kDa

Observed Molecular Weight

45 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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