Recombinant Aurora A Monoclonal Antibody
Product Specifications
Background
Aurora A (AURKA) Homo sapiens The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.
Abbreviation
Aurora A
UniProt
O14965
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human Aurora A protein
Target
ARK; AYK; IAK; AIRK; PPP1R; AURKA/AURKB/AURKC; PPP1R47; STK7; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6; AURKA; ARK-1; Aurora 2; Aurora A; Aurora kinase A; Aurora/IPL1 like kinase; Aurora/IPL1-related kinase 1; AURORA2; Aurora-related kinase 1; Breast tumor-amplified kinase; hARK1; IPL1 related kinase; MGC34538; OTTHUMP00000031340; OTTHUMP00000031341; OTTHUMP00000031342; OTTHUMP00000031343; OTTHUMP00000031344; OTTHUMP00000031345; OTTHUMP00000166071; OTTHUMP00000166072; Protein phosphatase 1; regulatory subunit 47; Serine/threonine kinase 15; Serine/threonine kinase 6; Serine/threonine-protein kinase 15; Serine/threonine-protein kinase 6; Serine/threonine-protein kinase aurora-A
Clonality
Monoclonal,Recombinant
Clone
10F12
Conjugation
Unconjugated
Applications
WB
Field of Research
Cell Biology; Signal Transduction; Epigenetics and Nuclear Signaling; Cancer
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:1000-5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product MSDS
https://789.bio/eb/g0ZWqIRg
Calculated Molecular Weight
45 kDa
Observed Molecular Weight
45 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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