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Recombinant MTCO2 Monoclonal Antibody

Product Specifications

Background

Cofactor:Copper A., disease:Defects in MT-CO2 are a cause of cytochrome c oxidase deficiency (COX deficiency) [MIM:220110]; also called mitochondrial complex IV deficiency. COX deficiency is a clinically heterogeneous disorder. The clinical features are ranging from isolated myopathy to severe multisystem disease, with onset from infancy to adulthood., disease:Defects in MT-CO2 are associated with tumor formation., Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1., similarity:Belongs to the cytochrome c oxidase subunit 2 family.

Abbreviation

MTCO2

UniProt

P00403

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human MTCO2 rabbit protein

Target

COX; Mtco; Cytochrome c oxidase subunit; MT-CO; MT CO; MT-CO2; COII; MTCO2; COX2; Cytochrome c oxidase II; Cytochrome c oxidase polypeptide II; Cytochrome c oxidase subunit 2; MT CO2; COXII; COX2; COX2; COXII; Cytochrome c oxidase II; MT-CO2; COII; COX2

Clonality

Monoclonal,Recombinant

Clone

10F7

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Signal Transduction; Cancer; Metabolism

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

IHC 1:200-1000; WB 1:1000-5000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product MSDS

https://789.bio/eb/aN4y8VJ2

Calculated Molecular Weight

26 kDa

Observed Molecular Weight

21 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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