Recombinant MTCO2 Monoclonal Antibody
Product Specifications
Background
Cofactor:Copper A., disease:Defects in MT-CO2 are a cause of cytochrome c oxidase deficiency (COX deficiency) [MIM:220110]; also called mitochondrial complex IV deficiency. COX deficiency is a clinically heterogeneous disorder. The clinical features are ranging from isolated myopathy to severe multisystem disease, with onset from infancy to adulthood., disease:Defects in MT-CO2 are associated with tumor formation., Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1., similarity:Belongs to the cytochrome c oxidase subunit 2 family.
Abbreviation
MTCO2
UniProt
P00403
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human MTCO2 rabbit protein
Target
COX; Mtco; Cytochrome c oxidase subunit; MT-CO; MT CO; MT-CO2; COII; MTCO2; COX2; Cytochrome c oxidase II; Cytochrome c oxidase polypeptide II; Cytochrome c oxidase subunit 2; MT CO2; COXII; COX2; COX2; COXII; Cytochrome c oxidase II; MT-CO2; COII; COX2
Clonality
Monoclonal,Recombinant
Clone
10F7
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Signal Transduction; Cancer; Metabolism
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:200-1000; WB 1:1000-5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
26 kDa
Observed Molecular Weight
21 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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