Recombinant SIRT1 Monoclonal Antibody

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.

SIR; HST; SIRT; Hsir; homolog-like; SIR2 like protein; Regulatory protein SIR2 homolog; NAD-dependent deacetylase sirtuin; Sirtuin (silent mating type information regulation 2 homolog) ; SIR2L; Hsirt;75SirT; sirtuin; SIRT1; SIR2; SIR2L1; SIR2alpha; sirtuin 1;75SirT1; Hsir2; Hsirt1; HST2; S.cerevisiae; NAD-dependent deacetylase sirtuin-1; Regulatory protein SIR2 homolog 1; SIR2 like protein 1; homolog-like 1; SirtT1 75 kDa fragment; Sirtuin (silent mating type information regulation 2 homolog) 1; SIR2; SIR2alpha; SIR2L1; sirtuin 1; homolog of; NAD dependent deacetylase sirtuin 1; NAD dependent protein deacetylase sirtuin 1; OTTHUMP00000198111; OTTHUMP00000198112; S. cerevisiae; SIR1; SIR2 like 1; SIR2-like protein 1; Sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae) ; Sirtuin type 1