Recombinant Rad21 Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.
Abbreviation
Rad21
UniProt
O60216
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human Rad21 protein
Target
MCD; SCC; hHR; NXP; RAD; CDLS; HRAD; KIAA; CDLS4; HR21; HRAD21; MCD1; NXP1; SCC1; hHR21; MGS; KIAA0078; RAD21; hHR21; HR21; HRAD21; MCD1; NXP1; SCC1
Clonality
Monoclonal,Recombinant
Clone
6G12
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cell Biology; Epigenetics and Nuclear Signaling; Cancer
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:200-1000; WB 1:1000-5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
72 kDa
Observed Molecular Weight
130 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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