Recombinant SP1 Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.
Abbreviation
Sp1
UniProt
P08047
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human SP1 protein
Target
Specificity protein; Transcription factor Sp; SP1; SP 1; Sp1 transcription factor; Specificity protein 1; Transcription factor Sp1; TSFP 1; TSFP1
Clonality
Monoclonal,Recombinant
Clone
6G11
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Epigenetics and Nuclear Signaling; Stem Cells; Metabolism
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:200-1000; WB 1:1000-5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
100 kDa
Observed Molecular Weight
100 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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