Recombinant Hexokinase II Monoclonal Antibody
Product Specifications
Background
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
Abbreviation
Hexokinase II
UniProt
P52789
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human Hexokinase II protein
Target
DKFZp686M; HXK; HK2; HKII; HXK2; hexokinase-2; DKFZp686M1669; Hexokinase 2; Hexokinase 2 muscle; Hexokinase type II; HK 2; HK II; HxK 2; Muscle form hexokinase; HXK II
Clonality
Monoclonal,Recombinant
Clone
1F10
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction; Cardiovascular; Cancer; Metabolism
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:1000-5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
102 kDa
Observed Molecular Weight
102 kDa
Isotype
IgG, κ
Available Sizes
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