Recombinant c-Myc Monoclonal Antibody

MYC (v-myc avian myelocytomatosis viral oncogene homolog) Homo sapiens The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

BHLHe; MYC BHLHE; MRTL; MYCC; bHLHe39; c-Myc; MYC; MYC BHLHE39; AU016757; Avian myelocytomatosis viral oncogene homolog; c Myc; Class E basic helix-loop-helix protein 39; Myc protein; Myc proto oncogene protein; Myc proto-oncogene protein; Myc2; myc-related translation/localization regulatory factor; Myelocytomatosis oncogene; Niard; Nird; Oncogene Myc; OTTHUMP00000158589; Proto-oncogene c-Myc; Protooncogene homologous to myelocytomatosis virus; RNCMYC; Transcription factor p64; Transcriptional regulator Myc-A; V-Myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog (avian) ; V-myc myelocytomatosis viral oncogene homolog (avian)