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Recombinant TATA Box Binding Protein Monoclonal Antibody

Product Specifications

Background

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus.

Abbreviation

TATA Box Binding Protein

UniProt

P20226

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human TATA Box Binding Protein protein

Target

HDL; SCA; TBP; GTF2D; GTF2D1; HDL4; SCA17; TFIID; TATA sequence-binding protein; Transcription initi; TF2D; GTF2D1; HDL4; SCA17; TATA sequence-binding protein; TBP; TFIID; BA2R; CCG1; CCGS; DYT3; DYT3/KAT4; MRXS33; N-NSCL2; P250; TAF (II) 250; TAF1; TAF2A; TAFII250; TAFII-250; TATA binding factor; TATA box binding protein; TATA box factor; TATA sequence binding protein; TATA-binding factor; TATA-binding protein; TATA-box binding protein; TATA-box binding protein associated factor 1; TATA-box factor; TATA-box-binding protein; Transcription initiation factor TFIID TBP subunit; XDP; TATA Binding Protein

Clonality

Monoclonal,Recombinant

Clone

7F14

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Epigenetics and Nuclear Signaling; Isotype; Loading Controls

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

IHC 1:400-1000; WB 1:1000-5000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

38 kDa

Observed Molecular Weight

38 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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