Recombinant TATA Box Binding Protein Monoclonal Antibody
Product Specifications
Background
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus.
Abbreviation
TATA Box Binding Protein
UniProt
P20226
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human TATA Box Binding Protein protein
Target
HDL; SCA; TBP; GTF2D; GTF2D1; HDL4; SCA17; TFIID; TATA sequence-binding protein; Transcription initi; TF2D; GTF2D1; HDL4; SCA17; TATA sequence-binding protein; TBP; TFIID; BA2R; CCG1; CCGS; DYT3; DYT3/KAT4; MRXS33; N-NSCL2; P250; TAF (II) 250; TAF1; TAF2A; TAFII250; TAFII-250; TATA binding factor; TATA box binding protein; TATA box factor; TATA sequence binding protein; TATA-binding factor; TATA-binding protein; TATA-box binding protein; TATA-box binding protein associated factor 1; TATA-box factor; TATA-box-binding protein; Transcription initiation factor TFIID TBP subunit; XDP; TATA Binding Protein
Clonality
Monoclonal,Recombinant
Clone
7F14
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Epigenetics and Nuclear Signaling; Isotype; Loading Controls
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:400-1000; WB 1:1000-5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
38 kDa
Observed Molecular Weight
38 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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