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Recombinant FAK Monoclonal Antibody

Product Specifications

Background

PTK2 (protein tyrosine kinase 2) Homo sapiens This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only four of them have been determined.

Abbreviation

FAK

UniProt

Q05397

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human FAK protein

Target

PTK; PPP1R; FADK; FAK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK; PTK2; FADK 1; FAK related non kinase polypeptide; Focal adhesion Kinase; Focal adhesion kinase 1; Focal adhesion kinase isoform FAK Del33; Focal adhesion kinase related nonkinase; Protein phosphatase 1 regulatory subunit 71; Protein tyrosine kinase 2; Protein-tyrosine kinase 2; PTK2 protein tyrosine kinase 2

Clonality

Monoclonal,Recombinant

Clone

5A11

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cardiovascular; Signal Transduction; Cancer

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

IHC 1:400-1:1000; WB 1:1000-1:5000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

119 kDa

Observed Molecular Weight

119 kDa

Isotype

IgG, κ

Available Sizes

Frequently Asked Questions

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