Recombinant Neurofilament heavy polypeptide Monoclonal Antibody
Product Specifications
Background
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.
Abbreviation
Neurofilament heavy polypeptide
UniProt
P12036
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human Neurofilament heavy polypeptide protein
Target
KIAA; CMT2CC; NFH; NEFH; NF H; NF-H;200 kDa neurofilament protein; Neurofilament heavy polypeptide; Neurofilament heavy polypeptide 200kDa; Neurofilament triplet H protein; KIAA0845; Heavy Polypeptide 200kDa; Neurofilament; Neurofilament Heavy; NF-H
Clonality
Monoclonal,Recombinant
Clone
5A6
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Neuroscience; Signal Transduction; Stem Cells; Developmental Biology
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:200-1:1000; WB 1:1000-1:5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
110 kDa
Observed Molecular Weight
180-200 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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