Recombinant GCLM Monoclonal Antibody
Product Specifications
Background
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
Abbreviation
GCLM
UniProt
P48507
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human GCLM protein
Target
GCLM; GLCLR; Gamma-ECS regulatory subunit; Gamma-glutamylcysteine synthetase regulatory subunit; GCS light chain; Glutamate--cysteine ligase modifier subunit
Clonality
Monoclonal,Recombinant
Clone
3P9
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Neuroscience; Signal Transduction; Cell Biology; Metabolism
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:200-1:500; WB 1:1000-1:5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
31 kDa
Observed Molecular Weight
31 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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