Recombinant MMP3 Monoclonal Antibody
Product Specifications
Background
MMP3 (matrix metallopeptidase 3) Homo sapiens Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Abbreviation
MMP3
UniProt
P08254
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human MMP3 protein
Target
STR; CHDS; Stromelysin; Matrix metalloproteinase; Transin; MMP; MMP3; CHDS6; MMP-3; SL-1; STMY; STMY1; STR1; Matrix metalloproteinase-3; Progelatinase; Stromelysin-1; Transin-1; MMP-3
Clonality
Monoclonal,Recombinant
Clone
3P7
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cardiovascular; Signal Transduction; Cancer; Cell Biology; Kits; Lysates; Other
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:200-1:1000; WB 1:1000-1:5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
54 kDa
Observed Molecular Weight
54 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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