Recombinant Fas Monoclonal Antibody

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis.

APT; TNR; CD antigen CD; Tumor necrosis factor receptor superfamily member; TNFRSF; APO; ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6; FAS; APO1; FASR; TNFRSF6 and FAS; TNR6; Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor; CD antigen CD95; APO-1; APT1; FASTM; TNFRSF6; ALPS 1A; APO 1; Apo 1 antigen; APO 1 cell surface antigen; Apo1 antigen; APO1 cell surface antigen; Apoptosis antigen 1; Apoptosis mediating surface antigen FAS; APT 1; CD 95; CD 95 antigen; CD95 antigen; Delta Fas; Delta Fas/APO 1/CD95; Delta Fas/APO1/CD95; Fas (TNF receptor superfamily; FAS 1; FAS 827dupA; Fas AMA; FAS Antigen; Fas cell surface death receptor; FAS/CD95; member 6; member 6) ; sFAS; Surface antigen APO1; TNF receptor superfamily; TNFRSF 6; CD95