Recombinant Rab 5A Monoclonal Antibody
Product Specifications
Background
Enzyme regulation:Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP., Required for the fusion of plasma membranes and early endosomes., similarity:Belongs to the small GTPase superfamily. Rab family., subcellular location:Enriched in stage I melanosomes., subunit:Binds EEA1. Interacts with RIN1 and GAPVD1, which regulate its pathway, probably by acting as a GEF. Interacts with ALS2CL, UNC84B, ZFYVE20 and RUFY1. Interacts with SGSM1 and SGSM3.
Abbreviation
Rab 5A
UniProt
P20339
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human Rab 5A protein
Target
RAB; RAB5A; RAB5; RAB 5; RAB 5A; RAB5A member RAS oncogene family; RAS associated protein RAB5A; Ras related protein Rab 5A; Ras-related protein Rab-5A
Clonality
Monoclonal,Recombinant
Clone
12B10
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Neuroscience; Tags & Cell Markers; Signal Transduction
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:1000-1:4000; WB 1:1000-1:5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
24 kDa
Observed Molecular Weight
24 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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