Recombinant TLS/FUS Monoclonal Antibody

This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.

ETM; ALS; POMP; HNRNPP; FUS; ALS6; ETM4; FUS1; HNRNPP2; POMP75; TLS; RNA-binding protein FUS; ALS6; ETM4; FUS1; HNRNPP2; POMP75; RNA-binding protein FUS; TLS;16) in malignant liposarcoma) ;16) malignant liposarcoma;75 kDa DNA pairing protein;75 kDa DNA-pairing protein; Amyotrophic lateral sclerosis 6; FUS CHOP; Fus like protein; Fused in sarcoma; Fusion (involved in t (12; Fusion derived from t (12; Fusion gene in myxoid liposarcoma; Heterogeneous nuclear ribonucleoprotein P2; hnRNP P2; Oncogene FUS; Oncogene TLS; RNA binding protein FUS; TLS CHOP; Translocated in liposarcoma; Translocated in liposarcoma protein