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Recombinant Survivin Monoclonal Antibody

Product Specifications

Background

This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Abbreviation

Survivin

UniProt

O15392

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human Survivin protein

Target

EPR; API; IAP; BIRC; Apoptosis Inhibitor; Baculoviral IAP Repeat-Containing Protein; API4; EPR-1; BIRC5; Survivin; Apoptosis Inhibitor 4; Apoptosis Inhibitor Survivin; Baculoviral IAP Repeat-Containing Protein 5; IAP4; Apoptosis inhibitor4; Baculoviral IAP repeat containing 5; Baculoviral IAP repeat containing protein 5; BIRC 5; BIRC5; API4; EPR 1; Survivin variant 3 alpha; SVV; TIAP

Clonality

Monoclonal,Recombinant

Clone

12B6

Conjugation

Unconjugated

Applications

WB

Field of Research

Cell Biology; Neuroscience; Cancer

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

WB 1:1000-1:5000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

16 kDa

Observed Molecular Weight

16 kDa

Isotype

IgG, κ

Available Sizes

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