Recombinant EpCAM Monoclonal Antibody
Product Specifications
Background
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.
Abbreviation
EpCAM
UniProt
P16422
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human EpCAM protein
Target
M4S; MIC; M1S; DIAR; TROP; HNPCC; GA733; TACSTD; EGP; EPCAM; DIAR5; EGP-2; EGP314; EGP40; ESA; HNPCC8; KS1/4; KSA; M4S1; MIC18; MK-1; TACSTD1; TROP1; Ep-CAM; epithelial cell adhesion molecule; GA733-2; M1S2; MK-1; KSA; EGP40; TROP1;17 1A;323/A3;35-KD glycoprotein; Adenocarcinoma associated antigen; Adenocarcinoma-associated antigen; Antigen identified by monoclonal AUA1; AUA1; CD326; CD326 antigen; Cell surface glycoprotein Trop 1; Cell surface glycoprotein Trop 2; Cell surface glycoprotein Trop-1; chromosome 4; CO 17A; CO17 1A; CO17A; EGP 2; EGP2; Ep CAM; EpCAM1; Epithelial Cell Adhesion Molecule Intracellular Domain (EpCAM-ICD) ; Epithelial cell surface antigen; Epithelial cellular adhesion molecule; Epithelial glycoprotein; Epithelial glycoprotein 1; Epithelial glycoprotein 314; EpithelialGlycoprotein; GA733 1; GA733 2; gastrointestinal tumor-associated antigen 2; gp4; hEGP 2; hEGP314; Human epithelial glycoprotein 2; KS 1/4 antigen; KS 1/4 antigen.KSA; Ly74; Lymphocyte antigen 74; M1S 1; Major gastrointestinal tumor associated protein GA733 2; Major gastrointestinal tumor-associated protein GA733-2; mEGP314; Membrane component; Membrane component chromosome 4 surface marker (35kD glycoprotein) ; MK 1; Protein 289A; surface marker; surface marker 1; TACD1; Tumor associated calcium signal transducer 1; Tumor associated calcium signal transducer 2 precursor; Tumor-associated calcium signal transducer 1
Clonality
Monoclonal,Recombinant
Clone
12B5
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Tags & Cell Markers
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:200-1:1000; WB 1:1000-1:5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
35 kDa
Observed Molecular Weight
40 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items