Recombinant PCNA Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
Abbreviation
PCNA
UniProt
P12004
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human PCNA protein
Target
MGC; ATLD; etID36690.; HGCN; fa28e; fb36g; PCNA; ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; MGC8367; Mutagen-sensitive 209 protein; OTTHUMP00000030189; OTTHUMP00000030190; Pcna/cyclin; PCNAR; Polymerase delta accessory protein; Proliferating cell nuclear antigen; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; MGC8367; Mutagen-sensitive 209 protein; OTTHUMP00000030189; OTTHUMP00000030190; PCNA; Pcna/cyclin; PCNAR; Polymerase delta accessory protein; Proliferating cell nuclear antigen; wu:fa28e03; wu:fb36g03
Clonality
Monoclonal,Recombinant
Clone
12B2
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cell Biology; Epigenetics and Nuclear Signaling; Tags & Cell Markers; Cancer; Isotype; Loading Controls
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:1000-1:4000; WB 1:1000-1:5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
29 kDa
Observed Molecular Weight
36 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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