Recombinant NRAS Monoclonal Antibody

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.

ALPS; HRAS; NRAS; ALPS4; CMNS; N-ras; NCMS; NRAS1; NS6; GTPase NRas; GTPase; HRAS1; RASN; Transforming protein N-Ras; AV095280; N ras; N ras protein part 4; Neuroblastoma RAS viral (v ras) oncogene homolog; OTTHUMP00000013879; OTTMUSP00000023521; Transforming protein N Ras; v ras neuroblastoma RAS viral oncogene homolog; N-RAS