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Recombinant Cytokeratin 8 Monoclonal Antibody

Product Specifications

Background

KRT8 (keratin 8) Homo sapiens This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.

Abbreviation

Cytokeratin 8

UniProt

P05787

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human Cytokeratin 8 protein

Target

CYK; KRT; CYK8; KRT8; CARD2; CARD2; CK 8; CK-8; CK8; CYK8; CYKER; Cytokeratin endo A; Cytokeratin-8; DreK8; EndoA; K2C8; K2C8; K8; Keratin 8; Keratin type II cytoskeletal 8; Keratin; type II cytoskeletal 8; Keratin-8; KO; Krt 2.8; KRT8; MGC118110; MGC174782; MGC53564; MGC85764; sb:cb186; Type-II keratin Kb8; CK 8; CK8; CK-8; CYKER; Cytokeratin endo A; Cytokeratin-8; DreK8; EndoA; K2C8; Keratin; Keratin 8; Keratin type II cytoskeletal 8; Keratin-8; Krt 2.8; MGC118110; MGC174782; MGC53564; MGC85764; sb:cb186; type II cytoskeletal 8; Type-II keratin Kb8

Clonality

Monoclonal,Recombinant

Clone

6F6

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Signal Transduction; Cancer

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

IHC 1:200-1:1000; WB 1:1000-1:5000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

54 kDa

Observed Molecular Weight

54 kDa

Isotype

IgG, κ

Available Sizes

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